The domain within your query sequence starts at position 1238 and ends at position 1293; the E-value for the RPT_1 domain shown below is 9.57e-6.

TDSEVHESASDKDSVSKGKLPKREERPENKKPVKPQSSFKPENHVRIDNRPLEKPY

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.