The domain within your query sequence starts at position 1240 and ends at position 1295; the E-value for the RPT_1 domain shown below is 2.14e-5.

TDSEVHESASDKDSVSKGKLPKREERPENKKPVKPQSSFKPENHVRIDNRPLEKPY

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.