The domain within your query sequence starts at position 1292 and ends at position 1410; the E-value for the RPT_1 domain shown below is 1.32e-16.

GHVCTRACHPYDSSHKEFQCMKPCQKVLCQDGHRCPNVCFQECQPCQVKVPKIILKCGHK
QMVPCSMSESEFCCQEPCSKILRCGHRCSHLCGEDCVRLCSERVTVELKCGHSQLVKCG

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.