The domain within your query sequence starts at position 154 and ends at position 349; the E-value for the RPT_1 domain shown below is 6.25e-15.

TSTSQAEGEPLTPQRFPTTASSSLQTPLEPPEISSTILATSQGSSVPYSTCDKSSRVPPV
TASSSTQTIQTCLATSTLPCSHQATLKSPKTEPSSVQATQMTQAIKASGHNCPQVPAAPV
SSSFIKPQVTPAMLLSGVQAPLMPQATVPSCAQTFEMNPATMTNGCNSPQMSAATVHSSY
SNPRVTPVTVASSGQS

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.