The domain within your query sequence starts at position 159 and ends at position 229; the E-value for the RPT_1 domain shown below is 8.6e-5.

HHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPSH
SGIAHPGHTER

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.