The domain within your query sequence starts at position 1609 and ends at position 1702; the E-value for the RPT_1 domain shown below is 2.38e-6.

SSSGSSPIQYLKRQTRSSPMLQHKISETIESRAHHKMKAGSPGSEVVTLQQFLEESNKLT
SIQLKSSSQENLLDEVMKSLSVSSDFLGKDKPVS

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.