The domain within your query sequence starts at position 172 and ends at position 298; the E-value for the RPT_1 domain shown below is 5.65e-42.

PEGREREGAQESLLPQEEAGSTGMDTSSPSDLPSSCGESQPFQVAQPRGAVQQEAPTQAG
NAGSMEPLLDQLLDEVQVEEPAPAPLNLDGDPGGRVHEGSQESFWPQEEAGSTGLDTSSP
SDSNSFC

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.