The domain within your query sequence starts at position 177 and ends at position 253; the E-value for the RPT_1 domain shown below is 7.97e-7.

QNSDDDEEKMQNTDDEDRAQISDDDRQQLSEEEKGNSDDEHPVASDNDEEKQNSDDEDQP
QVSDEEKMQNSDDERPQ

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.