The domain within your query sequence starts at position 1857 and ends at position 2050; the E-value for the RPT_1 domain shown below is 1.42e-9.

SDGGAVREKSYSNENGSVSLENGQRRKVSRKSSSDKESNLQVTQKSPKDRSSPSRITQRA
SVATDKMKLTSDAEDLSLESVCTRSKRRRKKPARFACTPAKTALSSEEKHAHCEVPEAQP
ACRNKLPEPEHQDSAENPSQAASADLNSGGGSSFEQRKSIQSRQMGAVCVRPPPKTQSSS
AGLSQENARSQTLD

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.