The domain within your query sequence starts at position 207 and ends at position 275; the E-value for the RPT_1 domain shown below is 5.53e-5.

QRVKGWAPRSGSEVGQTQQASTAAERAGEMRHSQASSDDDSSRNTGDRSDQMLGTRRWKP
KIKWVSLRR

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.