The domain within your query sequence starts at position 209 and ends at position 276; the E-value for the RPT_1 domain shown below is 2.42e-8.

FENAGFREDYSPPPEESVPFQVGGEEFGGDSPPPGLPRVIPQIGIGGEFPTVAVPSALCL
APAENAPP

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.