The domain within your query sequence starts at position 219 and ends at position 406; the E-value for the RPT_1 domain shown below is 7.79e-148.

KKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGGQNQAKKGEGAQNQG
KKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQSKKGEGAQNQA
KKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQ
AKKGEGGQ

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.