The domain within your query sequence starts at position 2583 and ends at position 2759; the E-value for the RPT_1 domain shown below is 1.57e-16.

RHVLASLLAEWPGHVPVSEDILELSGPAHMTYILDMFMQLEEKHQWEKILQKVLQGCREN
MLGTMALAACQFMEEPGMEVQVRESKHPYNNNTSFEDKVHIPGAIYLSIKFDPQCNTEEG
CDELAMSSSSDFQQDRHNFSGSQQKWKDFELPGDTLYYRFTSDMSNTEWGYRFTVTA

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.