The domain within your query sequence starts at position 263 and ends at position 394; the E-value for the RPT_1 domain shown below is 5.99e-5.

LCSPRGLAVSWLTGAIAVLEHPCAFGRTGCNNTRVKVFNSTMQLIGQVDSFGLNLLFPSK
VTASAVTFDHQGNVIVADTSGPAIVCLGKPEEFPALKPIITHGLSRPVALAFTKENSLLV
LDTASHSIKVFK

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.