The domain within your query sequence starts at position 2820 and ends at position 2885; the E-value for the RPT_1 domain shown below is 2.47e-5.

QRQRSPSGPRASLPTRDTSSGPTKASRHSPRSAAAGSPGKERSTSTPSSRLERSLTASQD
PEHSLT

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.