The domain within your query sequence starts at position 286 and ends at position 342; the E-value for the RPT_1 domain shown below is 7.28e-22.

KPYAEFLMPISKGGPRVIQLYPEFPMPISKGGPQKAQPDPKFPIPISKGGPQVAQPY

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.