The domain within your query sequence starts at position 302 and ends at position 398; the E-value for the RPT_1 domain shown below is 6.21e-27.

LPPAQSQTQEGGPAAGKASGADQRDTRRKAGPAWMVTRTEGHEETPLPPAQSQTQEGGPA
AGKASGADERDTRRKAGPAWMVRRSEGHEQTPAAHAQ

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.