The domain within your query sequence starts at position 312 and ends at position 525; the E-value for the RPT_1 domain shown below is 2.46e-5.

EEGLTSAQAQGPGCHEERSMSPVERQELLEKAYREATSQGNSSHRQLGVRRGSSLEEMTG
VSAGVEGSQQATPTLSAAPAGEAGTRLTGKMSAGVGRMARETASGQTAPDVGQAAPVRRD
PTESVPSEVSGEERRLGSGNSGSTKLLASGPSAGGSRTDTSGLLSPRGSNLEARKGKEMV
AENRNLLENAAQTDNTPAGVDSAFSTPAPLLHPE

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.