The domain within your query sequence starts at position 321 and ends at position 508; the E-value for the RPT_1 domain shown below is 8.09e-9.

VKVPTLDVAAPSMGVDLALPGAEVEAQGEVPEVALKMPRLSFPRFGIRGKEATEAKVVKG
SPEAKAKGPRLRMPTFGLSLLEPRPSGPEAVAESKLKLPTLKMPSFGIGVTGPEVKAPKG
PEVKLPKVPEVKLPKVPEAAIPDVQLPEVQLPKMSDMKLPKIPEMVVPDVRLPEVQLPKV
PEMKVPEM

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.