The domain within your query sequence starts at position 324 and ends at position 431; the E-value for the RPT_1 domain shown below is 4.47e-22.

RPLTSIWPPAVARPKNINMDSSSSLEHGHPHGLQLLTSPKDINTDSGCSRTTDPDMALSS
SMSPDTNMISGGGRGYTEWHGHLKLRSPQTPMWPQVAPQPTDVCMTSG

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.