The domain within your query sequence starts at position 337 and ends at position 442; the E-value for the RPT_1 domain shown below is 5.17e-20.

GFPGRPGLDGSKGEPGDPGRPGPVGEQGLMGFIGLVGEPGIVGEKGDRGVMGPPGAPGPK
GSMGHPGTPGGIGNPGEPGPWGPPGSRGLPGMRGAKGHRGPRGPDG

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.