The domain within your query sequence starts at position 343 and ends at position 476; the E-value for the RPT_1 domain shown below is 5.47e-6.

PPCTTKDYFQIHTPCDEEGKTQIMYKWIEPKICREDLTDAIRLPPSGEKKDCPPCNPGFY
NNGSSSCHPCPPGTFSDGTKECKSCPAGTEPALGFEYKWWNVLPANMKTSCFNVGNSKCD
GMNGWEVAGDHIRS

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.