The domain within your query sequence starts at position 366 and ends at position 420; the E-value for the RPT_1 domain shown below is 4.09e-5.

PGVRQPGSNSGSAPGQPNPGTARPTLSSGPVPRRQNGSSSSGPEQSAGGIRKLAS

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.