The domain within your query sequence starts at position 421 and ends at position 660; the E-value for the RPT_1 domain shown below is 8.87e-74.

EHTSQVTVSITEGSIVPGRTCGGQVVVPGRIGTGQVVMPGRECGGHVVMPGRGSGGQVTI
PGRGSGGQVTVPRGECGGQVTMPGRGSGGQVTMPGRGSGGQVTIPGRGSGGQVTVPGRGS
GGQVTIPGRGSGGQVTIPGRGSGGQVTVPGRGSGGQVTIPGRGSGGQVTIPGRESGGQVT
IPGRESGGQVTMPGREYGGQVTIPGRESGGQVTMPGRGSGGQVTMPGRGSGGQVTVPGRE

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.