The domain within your query sequence starts at position 490 and ends at position 607; the E-value for the RPT_1 domain shown below is 1.13e-8.

LTDLDVLKLELIPEAKIPAKISQMTNLQELHLCHCPAKVEQTAFSFLRDHLRCLHVKFTD
VAEIPAWVYLLKNLRELYLIGNLNSENNKMIGLESLRELRHLKILHVKSNLTKVPSNI

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.