The domain within your query sequence starts at position 528 and ends at position 618; the E-value for the RPT_1 domain shown below is 9.12e-8.

IHKSEKGNLFPNQEDKDTISESLEVTNEFHTADHSIRENVCDHEAQTTLGLRKSVNAQQN
LTKKTKQKINRGTKIVSSMKQIYEDNDKDMH

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.