The domain within your query sequence starts at position 543 and ends at position 625; the E-value for the RPT_1 domain shown below is 5.09e-18.

EEEHAPEPESIVHREEEHAPGPVPIVHREEEHVPELESIVHRGEEHAPEPIVHRDEGHAP
EPIVHREEEHVPEPIVHRDEGHA

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.