The domain within your query sequence starts at position 67 and ends at position 288; the E-value for the RPT_1 domain shown below is 7.56e-9.

VARKFLYLWIRVTFGRVTPSRARIFHEQKILQKVFGEWREEWWVSQREWKLCVRADCHYR
YYLYNLIFQNWKTFVHQQREMRKRFRIAEHHDTKQKMCQAWKSWLIYMVSRRTKLHMKTT
ALEFRRQSVLCFWWSKWRWRLGQAHAEHALHAVAVKHRALSLQLQGWLRWQEQLLISQRD
RRKEATAVQHYQHWQKQRSLKAWLKYLQICRVKRWQNEMAVQ

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.