The domain within your query sequence starts at position 746 and ends at position 879; the E-value for the RPT_1 domain shown below is 7.57e-6.

SVQFDMKLADVGGDLKHVMSDSSLDLPTVSGQHPPAAGSALASEDALPETAFPAFASFKD
MMPQTTEQKEFESGDFQDFTRQDMPTVDRSQETSCPSPASSVASHETPKEGADDFGEFQS
EKSKISKFDFLVAN

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.