The domain within your query sequence starts at position 1208 and ends at position 1347; the E-value for the RPT_2 domain shown below is 1.1e-5.

VSQSEISEPMAVPANYSMSESETSMLASEAVMTVPEPAREPESSVTSAPVESAVVAEHEM
VPERPMTYMVSETTMSVEPAVLTSEASVISETSETYDSMRPSGHAISEVTMSLLEPAVTI
SQPAENSLELPSMTVPAPST

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.