The domain within your query sequence starts at position 1247 and ends at position 1312; the E-value for the RPT_2 domain shown below is 7.75e-5.

GLLSGCSQSALQSTDVSLESKVSSLPASEKSRECERQVQELQSPVAAGQLQLTETEANHR
AETESL

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.