The domain within your query sequence starts at position 1468 and ends at position 1529; the E-value for the RPT_2 domain shown below is 1.96e-8.

PGAQGPPGFKGESGLPGQLGPPGKRGTEGGTGLPGNQGEPGSKGQPGDSGEMGFPGVAGL
FG

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.