The domain within your query sequence starts at position 1737 and ends at position 2197; the E-value for the RPT_2 domain shown below is 1.05e-58.

QAQDLGLTLTPEQAQDLGISLIPKQEISFSPLQAQAMGLTLTPQQAQVQKIYLTPQQAQA
LGITVSPEQAKGISLTPEEAHSLGIILTVEQAKAQRINLTPQQAQDLGLTLTPEQAQDLG
ISLIPKQQEISFSPLQAQAMGLTLTPQQAQVQKIYLTPQQAQALGITVSPEQAKGISLTP
EEAHSLGIILTVEQAKAQRINLTPQQAQDLGITLTPEQAQDLGISLIPKQQEISFSPLQA
QAMGLTLTPQQAQVQKIYLTPQQAQALGITVSPEQAKGISLTPEEAHSLGIALTVEQAKA
QRINLTPQQAQDLGLTLTPEQAQDLGIASTLKQAEAVGIIPTPTPEPYQERRLSLTSEQV
QALRTSFPTKETLSLGIYLTPKQAQYLGITLTASQAKVMKICLTPEQAQALGITVTPKQA
KARRTSLTPEQAQALGVILTPEQAQAHRITVTPEQAQALGI

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.