The domain within your query sequence starts at position 1813 and ends at position 1913; the E-value for the RPT_2 domain shown below is 2.32e-5.

SDSSRGPPTKDPAHASTPPGTKAVQTQQPCSVRASLSTDICSGLASDGGGARGQGSSTSS
LAPGPEPGPQPTLHVQAQVNNSNNKKGTFTDDLHKLVDEWT

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.