The domain within your query sequence starts at position 230 and ends at position 347; the E-value for the RPT_2 domain shown below is 7.36e-7.

REGHSGLSCGLEKNKYELNYIQLRKGGEQKLGYNTSSSGNSKIQSHVYGFSNSSGCCRPK
NASSSCQASRSQGQGNQSCRTQSNCQSGTSGGQGYGCVSEGQSSRCCQPKPRSCSQSS

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.