The domain within your query sequence starts at position 259 and ends at position 559; the E-value for the RPT_2 domain shown below is 1.83e-16.

PWFWPKDKTKVWSKPKEEPNSRSWFRSKKEVRVESTSGSECENPTKSLFWSGEEAKSRSK
PRARKGVNMRARQQAKREACSDAMSGAIDTNKKESWFLPEEKANVFSKSKTKKEPRTRAV
PKEEVKTKARASTKQEARPEEEVLVGAWFWDTQESTMADRISIKTTFVEEEPIVGDWFWS
EEEASVDSETCHTSRPRAKEEQVSSFCLGSGKKSSMESGPKATSKSMPVAKEDEVVIGSW
FWADDEEINLQADDESIFGSWFWGTGENSLRSVGVNCEKMPKAGEKEVTDSWFWAGDVNT
E

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.