The domain within your query sequence starts at position 275 and ends at position 397; the E-value for the RPT_2 domain shown below is 3.62e-8.

QLAPVKVREAATQPASGKVREAATQLAPVKVRKAATQLAPVKVHEAATQPAPGKVSDAAT
QSASVQVREAATQLSPVEATDTSQLAQVKADEAFAQHTSGEAHQVANGQSPIEVCETATG
QHS

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.