The domain within your query sequence starts at position 297 and ends at position 351; the E-value for the RPT_2 domain shown below is 2.47e-5.

VPKYRTPKERVSYHKASKDVSPEDTGTKDEAPEVKVLKKVVYKDRPQKDKAPEPR

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.