The domain within your query sequence starts at position 317 and ends at position 428; the E-value for the RPT_2 domain shown below is 7.28e-6.

GAAVVKVPTLDVAAPSMGVDLALPGAEVEAQGEVPEVALKMPRLSFPRFGIRGKEATEAK
VVKGSPEAKAKGPRLRMPTFGLSLLEPRPSGPEAVAESKLKLPTLKMPSFGI

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.