The domain within your query sequence starts at position 370 and ends at position 454; the E-value for the RPT_2 domain shown below is 2.15e-10.

NKGNKSIITKESGKLSGSKDSNGHQGVELDKRNSPKQGESDKPQGTAEKSAAHSNLGHSR
IGSSSNSDGHDSYEFDDESMQGDDP

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.