The domain within your query sequence starts at position 502 and ends at position 685; the E-value for the RPT_2 domain shown below is 1.17e-6.

QTMVQMQRSGDSQPQVNLFSSTKNIMSVQNNGTQQQGNSLFQQGSEMMSLQSGNFLQQSS
HSQAQLFHPQNPIADAQNLSQETQGSIFHSPNPIVHSQTSTASSEQLQPSMFHSQNTIAV
LQGSSVPQDQQSPNIFLSQSSINNLQTNTVAQEEQISFFAAQNSISPLQSTSNTEQQAAF
QQQP

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.