The domain within your query sequence starts at position 2329 and ends at position 2516; the E-value for the RPT_3 domain shown below is 6.78e-17.

LPPFSTSSVSPTDEIHITSTNPHTVSSVSMSRPVSTILQTTIEVTTPPNTSTPVTHSTSA
TTEAQGSFSTERTSTSYLSHPSSTTVHQSTAGPVITSIKSTMGVTGTPPVHTTSGTTSSP
QTPHSTHPISTAAISRTTGISGTPFRTPMKTTITFPTPSSLQTSMATLFPPFSTSVMSST
EIFNTPTN

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.