The domain within your query sequence starts at position 1209 and ends at position 1262; the E-value for the RPT_4 domain shown below is 3.07e-5.

SQVLPSLSPEHKEMPGSNIESSPEVEERPAVLSALDQSQSQPSKAAETPAVASC

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.