The domain within your query sequence starts at position 355 and ends at position 484; the E-value for the RPT_5 domain shown below is 3.07e-5.

SSTGPELPAPTPLLVEQHVDSPRPLAAIPSSQEPVNPSSEASPTRGCSPPKSPEKPPQST
SSESCPPSPQPTKGSRHASSSPESLKPTPAPGSRREISSSPTSKNRSHGRAKRDKSHSHT
PSHRAGRSRS

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.