The domain within your query sequence starts at position 222 and ends at position 420; the E-value for the d1a4ya_ domain shown below is 1e-9.

IQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIVTSSFGDSEKLDEEIIFSLISQLP
TLHCLQKLYVNHVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKH
LHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQLSHLREVSF
YDNNVSLPFLKQLLHHTAL

This is a SCOP domain - please see the SCOP entry of d1a4ya_ for further annotation