The domain within your query sequence starts at position 222 and ends at position 420; the E-value for the d1a4ya_ domain shown below is 5e-9.

IQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLP
TLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKH
LHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTF
YDNDVSLPFLKQLLHHTAL

This is a SCOP domain - please see the SCOP entry of d1a4ya_ for further annotation