The domain within your query sequence starts at position 247 and ends at position 445; the E-value for the d1a4ya_ domain shown below is 5e-9.

IQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLP
TLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKH
LHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTF
YDNDVSLPFLKQLLHHTAL

This is a SCOP domain - please see the SCOP entry of d1a4ya_ for further annotation