The domain within your query sequence starts at position 289 and ends at position 481; the E-value for the d1tubb2 domain shown below is 6e-25.
DLMEHLVPHPEFKMLGVRNIPQMSAASLAYSAFTWAGLLKHLRQMLISSAKMEEGINWQV RPPLTGLPPIGKASAHKEHHFNTSLANLVVLRGREVHSADVEGFKDPALYTSWLEPVDAF SVWKTQRAFDKYEKSAALVSNSQLLVKPLDMIVGKAWNMFSSKAFIHQYTKFGMEEEDFL DSFALLEQVVASY