TK Tachykinin family
SMART ACC:	SM000203
Description:	Tachykinins are a group of biologically active peptides which excite neurons, evoke behavioral responses, are potent vasodilatators and contract (directly or indirectly) many smooth muscles. These peptides are synthesized as longer precursors and then processed to peptides from ten to twelve residues long.
InterPro ACC:	IPR008215
InterPro abstract:	Tachykinins [ PUBMED:3284438 PUBMED:1969374 PUBMED:1324401 ] are a group of biologically active peptides which excite neurons, evoke behavioral responses, are potent … expand Tachykinins [ PUBMED:3284438 PUBMED:1969374 PUBMED:1324401 ] are a group of biologically active peptides which excite neurons, evoke behavioral responses, are potent vasodilatators and contract (directly or indirectly) many smooth muscles. This family includes many other peptides. Tachykinins, like most other active peptides, are synthesized as larger protein precursors, protachykinins, that are enzymatically converted to their mature forms. Tachykinins are from ten to twelve residues long. collapse
GO process:	tachykinin receptor signaling pathway (GO:0007217)
Family alignment:	View the Family alignment or the Alignment consensus sequence
There are 1 580 TK domains in 493 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing TK domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing TK domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a TK domain which could be assigned to a KEGG orthologous group, and not all proteins containing TK domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

Some of these KOs are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

3D structures in PDB containing this domain

Links to other resources describing this domain

PROSITE	TACHYKININ
InterPro	IPR008215