The domain within your query sequence starts at position 360 and ends at position 686; the E-value for the TR_FER domain shown below is 8.64e-193.

VKWCALSHLERTKCDEWSIISEGKIECESAETTEDCIEKIVNGEADAMTLDGGHAYIAGQ
CGLVPVMAEYYESSNCAIPSQQGIFPKGYYAVAVVKASDTSITWNNLKGKKSCHTGVDRT
AGWNIPMGMLYNRINHCKFDEFFSQGCAPGYEKNSTLCDLCIGPLKCAPNNKEEYNGYTG
AFRCLVEKGDVAFVKHQTVLDNTEGKNPAEWAKNLKQEDFELLCPDGTRKPVKDFASCHL
AQAPNHVVVSRKEKAARVKAVLTSQETLFGGSDCTGNFCLFKSTTKDLLFRDDTKCFVKL
PEGTTPEKYLGAEYMQSVGNMRKCSTS

TR_FER

Transferrin

• SMART accession number: SM00094
• Description: -
• Interpro abstract (IPR001156):

  Transferrins are eukaryotic iron-binding glycoproteins that control the level of free iron in biological fluids [ (PUBMED:3032619) ]. Evidence suggests that members of the TF family arose from the duplication and fusion of two homologous domains, with each duplicated domain binding one iron atom. Members of the family include blood serotransferrin (siderophilin); milk lactotransferrin (lactoferrin); egg white ovotransferrin (conalbumin); and membrane-associated melanotransferrin. Family members that do not bind iron have also been discovered, including inhibitor of carbonic anhydrase (ICA), which strongly binds to and inhibits certain isoforms of carbonic anhydrase [ (PUBMED:20572014) ].

  This entry represents the transferrin-like domain, which can be further divided into two subdomains that form a cleft inside of which the iron atom is bound in iron-transporting transferrin [ (PUBMED:2585506) ]. The iron-coordinating residues consist of an aspartic acid, two tyrosines and a histidine, as well as an arginine that coordinates a requisite anion. In addition to iron and anion liganding residues, the transferrin-like domain contains conserved cysteine residues involved in disulphide bond formation.

There are 4096 TR_FER domains in 2538 proteins in SMART's nrdb database.

Literature (relevant references for this domain)

Primary literature is listed below; Automatically-derived, secondary literature is also avaliable.

• Anderson BF, Baker HM, Norris GE, Rice DW, Baker EN
• Structure of human lactoferrin: crystallographic structure analysis and refinement at 2.8 A resolution.
• J Mol Biol. 1989; 209: 711-34

The structure of human lactoferrin has been refined crystallographically at 2.8 A (1 A = 0.1 nm) resolution using restrained least squares methods. The starting model was derived from a 3.2 A map phased by multiple isomorphous replacement with solvent flattening. Rebuilding during refinement made extensive use of these experimental phases, in combination with phases calculated from the partial model. The present model, which includes 681 of the 691 amino acid residues, two Fe3+, and two CO3(2-), gives an R factor of 0.206 for 17,266 observed reflections between 10 and 2.8 A resolution, with a root-mean-square deviation from standard bond lengths of 0.03 A. As a result of the refinement, two single-residue insertions and one 13-residue deletion have been made in the amino acid sequence, and details of the secondary structure and tertiary interactions have been clarified. The two lobes of the molecule, representing the N-terminal and C-terminal halves, have very similar folding, with a root-mean-square deviation, after superposition, of 1.32 A for 285 out of 330 C alpha atoms; the only major differences being in surface loops. Each lobe is subdivided into two dissimilar alpha/beta domains, one based on a six-stranded mixed beta-sheet, the other on a five-stranded mixed beta-sheet, with the iron site in the interdomain cleft. The two iron sites appear identical at the present resolution. Each iron atom is coordinated to four protein ligands, 2 Tyr, 1 Asp, 1 His, and the specific Co3(2-), which appears to bind to iron in a bidentate mode. The anion occupies a pocket between the iron and two positively charged groups on the protein, an arginine side-chain and the N terminus of helix 5, and may serve to neutralize this positive charge prior to iron binding. A large internal cavity, beyond the Arg side-chain, may account for the binding of larger anions as substitutes for CO3(2-). Residues on the other side of the iron site, near the interdomain crossover strands could provide secondary anion binding sites, and may explain the greater acid-stability of iron binding by lactoferrin, compared with serum transferrin. Interdomain and interlobe interactions, the roles of charged side-chains, heavy-atom binding sites, and the construction of the metal site in relation to the binding of different metals are also discussed.

• Crichton RR, Charloteaux-Wauters M
• Iron transport and storage.
• Eur J Biochem. 1987; 164: 485-506

Disease (disease genes where sequence variants are found in this domain)

SwissProt sequences and OMIM curated human diseases associated with missense mutations within the TR_FER domain.

Protein	Disease
Serotransferrin (P02787) (SMART)	OMIM:190000: Atransferrinemia OMIM:209300:

Structure (3D structures containing this domain)

3D Structures of TR_FER domains in PDB

PDB code	Title
1a8e	HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE
1a8f	HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE
1aiv	APO OVOTRANSFERRIN
1aov	APO DUCK OVOTRANSFERRIN
1b0l	RECOMBINANT HUMAN DIFERRIC LACTOFERRIN
1b1x	STRUCTURE OF DIFERRIC MARE LACTOFERRIN AT 2.62A RESOLUTION
1b3e	HUMAN SERUM TRANSFERRIN, N-TERMINAL LOBE, EXPRESSED IN PICHIA PASTORIS
1b7u	Structure of Mare Apolactoferrin: the N and C Lobes are in the Closed Form
1b7z	STRUCTURE OF OXALATE SUBSTITUTED DIFERRIC MARE LACTOFERRIN FROM COLOSTRUM
1biy	STRUCTURE OF DIFERRIC BUFFALO LACTOFERRIN
1bka	OXALATE-SUBSTITUTED DIFERRIC LACTOFERRIN
1blf	STRUCTURE OF DIFERRIC BOVINE LACTOFERRIN AT 2.8 ANGSTROMS RESOLUTION
1bp5	HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE, APO FORM
1btj	HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE, APO FORM, CRYSTAL FORM 2
1cb6	STRUCTURE OF HUMAN APOLACTOFERRIN AT 2.0 A RESOLUTION.
1ce2	STRUCTURE OF DIFERRIC BUFFALO LACTOFERRIN AT 2.5A RESOLUTION
1d3k	HUMAN SERUM TRANSFERRIN
1d4n	HUMAN SERUM TRANSFERRIN
1dot	CRYSTALLOGRAPHIC STRUCTURE OF DUCK OVOTRANSFERRIN AT 2.3 ANGSTROMS RESOLUTION
1dsn	D60S N-TERMINAL LOBE HUMAN LACTOFERRIN
1dtg	HUMAN TRANSFERRIN N-LOBE MUTANT H249E
1dtz	STRUCTURE OF CAMEL APO-LACTOFERRIN DEMONSTRATES ITS DUAL ROLE IN SEQUESTERING AND TRANSPORTING FERRIC IONS SIMULTANEOUSLY:CRYSTAL STRUCTURE OF CAMEL APO-LACTOFERRIN AT 2.6A RESOLUTION.
1eh3	R210K N-TERMINAL LOBE HUMAN LACTOFERRIN
1f9b	MELANIN PROTEIN INTERACTION: X-RAY STRUCTURE OF THE COMPLEX OF MARE LACTOFERRIN WITH MELANIN MONOMERS
1fck	STRUCTURE OF DICERIC HUMAN LACTOFERRIN
1fqe	CRYSTAL STRUCTURES OF MUTANT (K206A) THAT ABOLISH THE DILYSINE INTERACTION IN THE N-LOBE OF HUMAN TRANSFERRIN
1fqf	CRYSTAL STRUCTURES OF MUTANT (K296A) THAT ABOLISH THE DILYSINE INTERACTION IN THE N-LOBE OF HUMAN TRANSFERRIN
1gv8	18 kDa fragment of N-II domain of duck ovotransferrin
1gvc	18kDa N-II domain fragment of duck ovotransferrin + NTA
1h43	R210E N-TERMINAL LOBE HUMAN LACTOFERRIN
1h44	R210L N-TERMINAL LOBE HUMAN LACTOFERRIN
1h45	R210G N-TERMINAL LOBE HUMAN LACTOFERRIN
1h76	The crystal structure of diferric porcine serum transferrin
1hse	H253M N TERMINAL LOBE OF HUMAN LACTOFERRIN
1i6b	STRUCTURE OF EQUINE APOLACTOFERRIN AT 3.2 A RESOLUTION USING CRYSTALS GROWN AT 303K
1i6q	Formation of a protein intermediate and its trapping by the simultaneous crystallization process: Crystal structure of an iron-saturated intermediate in the FE3+ binding pathway of camel lactoferrin at 2.7 resolution
1iej	OVOTRANSFERRIN, N-TERMINAL LOBE, HOLO FORM, AT 1.65 A RESOLUTION
1iq7	Ovotransferrin, C-Terminal Lobe, Apo Form
1jnf	Rabbit serum transferrin at 2.6 A resolution.
1jqf	Human Transferrin N-Lobe Mutant H249Q
1jw1	Crystallization and structure determination of goat lactoferrin at 4.0 resolution: A new form of packing in lactoferrins with a high solvent content in crystals
1l5t	Crystal Structure of a Domain-Opened Mutant (R121D) of the Human Lactoferrin N-lobe Refined From a Merohedrally-Twinned Crystal Form.
1lcf	CRYSTAL STRUCTURE OF COPPER-AND OXALATE-SUBSTITUTED HUMAN LACTOFERRIN AT 2.0 ANGSTROMS RESOLUTION
1lct	STRUCTURE OF THE RECOMBINANT N-TERMINAL LOBE OF HUMAN LACTOFERRIN AT 2.0 ANGSTROMS RESOLUTION
1lfg	MOLECULAR REPLACEMENT SOLUTION OF THE STRUCTURE OF APOLACTOFERRIN, A PROTEIN DISPLAYING LARGE-SCALE CONFORMATIONAL CHANGE
1lfh	MOLECULAR REPLACEMENT SOLUTION OF THE STRUCTURE OF APOLACTOFERRIN, A PROTEIN DISPLAYING LARGE-SCALE CONFORMATIONAL CHANGE
1lfi	METAL SUBSTITUTION IN TRANSFERRINS: THE CRYSTAL STRUCTURE OF HUMAN COPPER-LACTOFERRIN AT 2.1 ANGSTROMS RESOLUTION
1lgb	INTERACTION OF A LEGUME LECTIN WITH THE N2 FRAGMENT OF HUMAN LACTOTRANSFERRIN OR WITH THE ISOLATED BIANTENNARY GLYCOPEPTIDE: ROLE OF THE FUCOSE MOIETY
1n04	Diferric chicken serum transferrin at 2.8 A resolution.
1n76	CRYSTAL STRUCTURE OF HUMAN SEMINAL LACTOFERRIN AT 3.4 A RESOLUTION
1n7w	Crystal Structure of Human Serum Transferrin, N-Lobe L66W mutant
1n7x	HUMAN SERUM TRANSFERRIN, N-LOBE Y45E MUTANT
1n84	HUMAN SERUM TRANSFERRIN, N-LOBE
1nft	OVOTRANSFERRIN, N-TERMINAL LOBE, IRON LOADED OPEN FORM
1nkx	CRYSTAL STRUCTURE OF A PROTEOLYTICALLY GENERATED FUNCTIONAL MONOFERRIC C-LOBE OF BOVINE LACTOFERRIN AT 1.9A RESOLUTION
1nnt	STRUCTURAL EVIDENCE FOR A PH-SENSITIVE DI-LYSINE TRIGGER IN THE HEN OVOTRANSFERRIN N-LOBE: IMPLICATIONS FOR TRANSFERRIN IRON RELEASE
1oqg	Crystal structure of the D63E mutant of the N-lobe human transferrin
1oqh	Crystal Structure of the R124A mutant of the N-lobe human transferrin
1ovb	THE MECHANISM OF IRON UPTAKE BY TRANSFERRINS: THE STRUCTURE OF AN 18KD NII-DOMAIN FRAGMENT AT 2.3 ANGSTROMS RESOLUTION
1ovt	REFINED CRYSTALLOGRAPHIC STRUCTURE OF HEN OVOTRANSFERRIN AT 2.4 ANGSTROMS RESOLUTION
1qjm	CRYSTAL STRUCTURE OF A COMPLEX OF LACTOFERRIN WITH A LANTHANIDE ION (SM3+) AT 3.4 ANSTROM RESOLUTION
1ryo	Human serum transferrin, N-lobe bound with oxalate
1ryx	Crystal structure of hen serum transferrin in apo- form
1sdx	Crystal structure of the zinc saturated C-terminal half of bovine lactoferrin at 2.0 A resolution reveals two additional zinc binding sites
1sqy	Structure of human diferric lactoferrin at 2.5A resolution using crystals grown at pH 6.5
1suv	Structure of Human Transferrin Receptor-Transferrin Complex
1tfa	OVOTRANSFERRIN, N-TERMINAL LOBE, APO FORM
1tfd	HIGH-RESOLUTION X-RAY STUDIES ON RABBIT SERUM TRANSFERRIN: PRELIMINARY STRUCTURE ANALYSIS OF THE N-TERMINAL HALF-MOLECULE AT 2.3 ANGSTROMS RESOLUTION
1vfd	HUMAN LACTOFERRIN, N-TERMINAL LOBE MUTANT WITH ARG 121 REPLACED BY GLU (R121E)
1vfe	HUMAN LACTOFERRIN, N-TERMINAL LOBE MUTANT WITH ARG 121 REPLACED BY SER (R121S)
2alu	Detection of new binding site in the C-terminal lobe of lactoferrin:Crystal structure of the complex formed between bovine lactoferrin and a tetrasaccharide at 2.1A resolution
2ays	A conserved non-metallic binding site in the C-terminal lobe of lactoferrin: Structure of the complex of C-terminal lobe of bovine lactoferrin with N-acetyl galactosamine at 1.86 A resolution
2b65	Crystal structure of the complex of C-lobe of bovine lactoferrin with maltose at 1.5A resolution
2bjj	Structure of recombinant human lactoferrin produced in the milk of transgenic cows
2d3i	Crystal Structure of Aluminum-Bound Ovotransferrin at 2.15 Angstrom Resolution
2doj	Crystal structure of the complex of C-terminal lobe of bovine lactoferrin with adenosine at 2.4 A resolution
2dp8	Carbohydrate recognition by lactoferrin: Crystal structure of the complex of C-terminal lobe of bovine lactoferrin with trisaccharide at 2.5 A resolution
2dqv	Structure of the C-terminal lobe of bovine lactoferrin in complex with galactose at 2.7 A resolution
2ds9	Structure of the complex of C-terminal lobe of bovine lactoferrin with mannose at 2.8 A resolution
2dsf	Structure of the complex of C-terminal lobe of bovine lactoferrin with xylose at 2.8A resolution
2dvc	Structure of the bovine lactoferrin C-lobe complex with sucrose at 3.0 A resolution
2dwa	Structure of the complex of lactoferrin C-terminal half with fucose at 2.07 A resolution
2dwh	Crystal structure of N-acetylglucosamine complex of bovine lactoferrin C-lobe at 2.8 A resolution
2dwi	Crystal structure of the complex formed between C-terminal half of bovine lactoferrin and cellobiose at 2.2 A resolution
2dwj	Structure of the complex of C-terminal lobe of bovine lactoferrin with raffinose at 2.3 A resolution
2dxr	Crystal structure of the complex formed between C-terminal half of bovine lactoferrin and sorbitol at 2.85 A resolution
2dxy	Structure of the complex of C-terminal lobe of bovine lactoferrin with trehalose at 2.0 A resolution
2dyx	Structure of the complex of lactoferrin C-lobe with melibiose at 2.0 A resolution
2e0s	Carbohydrate recognition of C-terminal half of lactoferrin: Crystal structure of the complex of C-lobe with rhamnose at 2.15 A resolution
2e1s	Crystal structure of the complex of C-terminal half of bovine lactoferrin and arabinose at 2.7 A resolution
2fa7	Crystal structure of the complex of bovine lactoferrin C-lobe with a pentasaccharide at 2.38 A resolution
2g93	Ligand recognition site in C-lobe of lactoferrin: Crystal structure of the complex of C-lobe of bovine lactoferrin with methyl alpha-D-mannopyranoside at 1.9 A resolution
2h4i	Crystal structure of the complex of proteolytically produced C-terminal half of bovine lactoferrin with lactose at 2.55 A resolution
2hau	Apo-Human Serum Transferrin (Non-Glycosylated)
2hav	Apo-Human Serum Transferrin (Glycosylated)
2hca	Crystal structure of bovine lactoferrin C-lobe liganded with Glucose at 2.8 A resolution
2nuv	Crystal structure of the complex of C-terminal lobe of bovine lactoferrin with atenolol at 2.25 A resolution
2nwj	Structure of the complex of C-terminal lobe of bovine lactoferrin with disaccharide at 1.75 A resolution
2o1l	Structure of a complex of C-terminal lobe of bovine lactoferrin with disaccharide at 1.97 A resolution
2o51	Crystal structure of bovine C-lobe with fructose at 3.0 A resolution
2o7u	Crystal structure of K206E/K296E mutant of the N-terminal half molecule of human transferrin
2o84	Crystal structure of K206E mutant of N-lobe human transferrin
2ocu	Structure of the complex of C-terminal lobe of bovine lactoferrin with N-(4-hydroxyphenyl) acetamide at 2.38 A resolution
2p1s	Crystal structure of the C-terminal lobe of bovine lactoferrin complexed with O-alpha-D-Glucopyranosyl-(1 3)-alpha-D-fructofuranosyl- (2 1)- alpha-D-glucopyranoside at 1.93 A resolution
2pms	Crystal structure of the complex of human lactoferrin N-lobe and lactoferrin-binding domain of pneumococcal surface protein A
2px1	crystal structure of the complex of bovine lactoferrin C-lobe with Ribose at 2.5 A resolution
2q8j	Crystal Structure of the complex of C-lobe of bovine lactoferrin with Mannitol and Mannose at 2.7 A resolution
2qje	Crystal structure of the complex of Bovine C-lobe with Amygdalin at 2.3A resolution
2r71	Crystal structure of the complex of bovine C-lobe with inositol at 2.1A resolution
2r9j	Ligand recognition in C-lobe: The crystal structure of the complex of lactoferrin C-lobe with nicotinamide at 2.5 A resolution
2zmb	Crystal structure of the complex of C-terminal lobe of bovine lactoferrin with parecoxib at 2.9 A resolution
3cfl	Crystal structure of the complex formed between C-lobe of bovine lactoferrin and 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine at 2.25 A resolution
3ci8	Crystal structure of the complex of C-lobe of lactoferrin with vitamin B3 (niacin) at 2.4 A resolution
3cr9	Crystal structure of the complex of Lactoferrin with 6-(Hydroxymethyl)oxane-2,3,4,5-tetrol at 3.49 A resolution
3crb	Crystal structure of the complex of C-lobe of lactoferrin with 2-chromenone at 2.6 A resolution
3e9x	Crystal Structure of the Complex of C-lobe of Lactoferrin with Nimesulide at 2.7 A Resolution
3fgs	Crystal structure of G65R/K206E double mutant of the N-lobe human transferrin
3iaz	Structural basis of the prevention of NSAID-induced damage of the gastrointestinal tract by C-terminal half (C-lobe) of bovine colostrum protein lactoferrin: Binding and structural studies of the C-lobe complex with aspirin
3ib0	Structural basis of the prevention of NSAID-induced damage of the gastrointestinal tract by C-terminal half (C-lobe) of bovine colostrum protein lactoferrin: Binding and structural studies of C-lobe complex with diclofenac
3ib1	Structural basis of the prevention of NSAID-induced damage of the gastrointestinal tract by C-terminal half (C-lobe) of bovine colostrum protein lactoferrin: Binding and structural studies of C-lobe complex with indomethacin
3ib2	structure of the complex of C-terminal half (C-lobe) of bovine lactoferrin with alpha-methyl-4-(2-methylpropyl) benzene acetic acid
3k0v	Removal of sugars and sugars-like molecules from the solution by C-lobe of lactoferrin: Crystal structure of the complex of C-lobe with beta-D-glucopyranosyl-(1->4)-beta-D-galactopyranosyl-(1->4)-alpha-D-glucopyranose at 1.9 A resolution
3kj7	Crystal Structure of the Complex of C-lobe of Bovine Lactoferrin with Dextrin at 1.9 A Resolution
3mc2	Crystal Structure of the Murine Inhibitor of Carbonic Anhydrase
3mjn	Crystal Structure of the complex of C-lobe of lactoferrin with isopropylamino-3-(1-naphthyloxy)propan-2-ol at 2.38 A Resolution
3o97	Crystal Structure of the complex of C-lobe of lactoferrin with indole acetic acid at 2.68 A Resolution
3qyt	Diferric bound human serum transferrin
3rgy	Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Lipopolysaccharide at 2.0 A Resolution
3s9l	Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, cryocooled 2
3s9m	Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, cryocooled 1
3s9n	Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, room temperature
3sdf	Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Lipoteichoic acid at 2.1 A Resolution
3skp	The structure of apo-human transferrin C-lobe with bound sulfate ions
3taj	Crystal structure of C-lobe of bovine lactoferrin complexed with Nabumetone at 1.7A resolution
3tod	Crystal Structure of C-lobe of Bovine lactoferrin Complexed with 1-Butyl-1H-Pyrazole-5-carboxylic acid at 1.38 A Resolution
3ttr	Crystal structure of C-lobe of bovine lactoferrin complexed with Lidocaine at 2.27 A resolution
3tus	Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Meta-hydroxy benzoic acid at 2.5 A Resolution
3u72	Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Isoniazid at 2.2 A Resolution
3u8q	Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Phenyl-Propanolamine at 1.97 A Resolution
3ugw	Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Deoxycytidine at 1.87 A Resolution
3uk4	Crystal Structure of C-lobe of Bovine lactoferrin Complexed with 1,2,5-Pentanetriol at 1.98 A Resolution
3usd	Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Imidazol (1,2 a) pyridine3-yl-acitic acid at 2.4 A Resolution
3v5a	Crystal Structure of C-lobe of Bovine Lactoferrin Complexed with Gamma Amino Butyric Acid at 1.44 A Resolution
3v83	The 2.1 angstrom crystal structure of diferric human transferrin
3v89	The crystal structure of transferrin binding protein A (TbpA) from Neisseria meningitidis serogroup B in complex with the C-lobe of human transferrin
3v8x	The crystal structure of transferrin binding protein A (TbpA) from Neisserial meningitidis serogroup B in complex with full length human transferrin
3vdf	Crystal Structure of C-lobe of Bovine lactoferrin Complexed with diaminopimelic acid at 1.46 A Resolution
3ve1	The 2.9 angstrom crystal structure of Transferrin binding protein B (TbpB) from serogroup B M982 Neisseria meningitidis in complex with human transferrin
4dig	Crystal Structure of C-lobe of Bovine lactoferrin Complexed with N-acetylmuramyl l-alanyl d-isoglutamine at 1.8 A Resolution
4dxu	Crystal Structure of C-lobe of Bovine lactoferrin Complexed with aminocaproic acid at 1.46 A Resolution
4fim	Crystal Structure of C-lobe of Bovine lactoferrin Complexed with celecoxib acid at 1.80 A Resolution
4fjp	Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Naproxen at 1.68 A Resolution
4for	Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Flurbiprofen at 1.58 A Resolution
4g2z	Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Mefenamic acid at 1.90 A Resolution
4g77	Crystal Structure of C-lobe of Bovine lactoferrin Complexed with tolfenamic acid at 1.98 A Resolution
4g8h	Crystal structure of C-lobe of bovine lactoferrin complexed with licofelone at 1.88 A resolution
4grk	Crystal Structure of C-lobe of Bovine lactoferrin Complexed with ketorolac at 1.68 A Resolution
4h0w	Bismuth bound human serum transferrin
4n6p	Crystal Structure of C-lobe of Bovine lactoferrin complexed with meclofenamic acid at 1.4 A resolution
4ned	Crystal STRUCTURE OF C-LOBE OF BOVINE LACTOFERRIN COMPLEXED WITH FENOPROFEN AT 2.1 ANGSTROM RESOLUTION
4oqo	Crystal structure of the tryptic generated iron-free C-lobe of bovine Lactoferrin at 2.42 Angstrom resolution
4x1b	4X1B
4x1d	4X1D
5cry	5CRY
5dyh	5DYH
5hbc	5HBC

Links (links to other resources describing this domain)

• INTERPRO: IPR001156
• PROSITE: PS00207